| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Immunology, Vol 131, Issue 6 2805-2809, Copyright © 1983 by American Association of Immunologists
ARTICLES |
WF Hickey, NK Gonatas, H Kimura and DB Wilson
Monoclonal antibodies specific for different rat T cell subsets and Ia- positive cells were used in a quantitative morphologic study of the cellular infiltrates in the spinal cords of Lewis rats during acute, actively induced experimental allergic encephalomyelitis (EAE). The predominant cell types in the inflammatory spinal cord lesions are W3/25-positive and Ia-positive cells. The relative percentages represented by each cell type remain quite constant regardless of the degree of clinical illness exhibited by the rat. These data demonstrate a quantitative profile of the infiltrating cells in acute, active EAE, and suggest that the principal inflammatory cells in these lesions are T helper cells and Ia-bearing cells (macrophages, B cells, or activated T helper cells).
This article has been cited by other articles:
|
|
 |
|
  T. Kielian, A. Cheung, and W. F. Hickey Diminished Virulence of an Alpha-Toxin Mutant of Staphylococcus aureus in Experimental Brain Abscesses Infect. Immun., November 1, 2001; 69(11): 6902 - 6911. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. S. Ousman and S. David MIP-1{alpha}, MCP-1, GM-CSF, and TNF-{alpha} Control the Immune Cell Response That Mediates Rapid Phagocytosis of Myelin from the Adult Mouse Spinal Cord J. Neurosci., July 1, 2001; 21(13): 4649 - 4656. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. T. Fife, K. J. Kennedy, M. C. Paniagua, N. W. Lukacs, S. L. Kunkel, A. D. Luster, and W. J. Karpus CXCL10 (IFN-{{gamma}}-Inducible Protein-10) Control of Encephalitogenic CD4+ T Cell Accumulation in the Central Nervous System During Experimental Autoimmune Encephalomyelitis J. Immunol., June 15, 2001; 166(12): 7617 - 7624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kielian, B. Barry, and W. F. Hickey CXC Chemokine Receptor-2 Ligands Are Required for Neutrophil-Mediated Host Defense in Experimental Brain Abscesses1 J. Immunol., April 1, 2001; 166(7): 4634 - 4643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Kielian and W. F. Hickey Proinflammatory Cytokine, Chemokine, and Cellular Adhesion Molecule Expression during the Acute Phase of Experimental Brain Abscess Development Am. J. Pathol., August 1, 2000; 157(2): 647 - 658. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Hornig, H. Weissenbock, N. Horscroft, and W. I. Lipkin An infection-based model of neurodevelopmental damage PNAS, October 12, 1999; 96(21): 12102 - 12107. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Rassnick, L. W. Enquist, A. F. Sved, and J. P. Card Pseudorabies Virus-Induced Leukocyte Trafficking into the Rat Central Nervous System J. Virol., November 1, 1998; 72(11): 9181 - 9191. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. J. Karpus and R. M. Ransohoff Cutting Edge Commentary: Chemokine Regulation of Experimental Autoimmune Encephalomyelitis: Temporal and Spatial Expression Patterns Govern Disease Pathogenesis J. Immunol., September 15, 1998; 161(6): 2667 - 2671. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Hickey and H Kimura Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo Science, January 15, 1988; 239(4837): 290 - 292. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
