The JI Acurri Cytometers
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Greene, M. I.
Right arrow Articles by Benjamin, T. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Greene, M. I.
Right arrow Articles by Benjamin, T. L.

The Journal of Immunology, Vol 128, Issue 2 732-736, Copyright © 1982 by American Association of Immunologists

ARTICLES

Specific thymus-derived (T) cell recognition of papova virus- transformed cells

MI Greene, LL Perry, E Kinney-Thomas and TL Benjamin

As a first step toward identifying papova virus-specific transplantation antigens and characterizing the immune response to these antigens, a series of congenic B10 mouse lines transformed by polyoma virus and SV40 has been obtained. B10.D2 (H-2d) mice immunized with x-irradiated polyoma-transformed B10.D2 cells (PyB10.D2) contained within their spleens a population of T cells that upon restimulation in vitro preferentially lyse 51Cr-labeled PyB10.D2 compared with other allogeneic polyoma-transformed target cells or SV40-transformed B10.D2 cells. Twenty hours after acute infection with polyoma virus, SV10.D2 cells express cell surface structures recognizable by polyoma-specific CTL. This CTL activity is therefore both polyoma specific and H-2 restricted, indicating associative recognition of H-2 molecules along with the virus-specific antigen.


This article has been cited by other articles:


Home page
 J. Immunol.Home page
A. E. Lukacher and C. S. Wilson
Resistance to Polyoma Virus-Induced Tumors Correlates with CTL Recognition of an Immunodominant H-2Dk-Restricted Epitope in the Middle T Protein
J. Immunol., February 15, 1998; 160(4): 1724 - 1734.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1982 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1982 by The American Association of Immunologists, Inc. All rights reserved.