The JI PBL Intereron Source
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pure, E.
Right arrow Articles by Vitetta, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pure, E.
Right arrow Articles by Vitetta, E.

The Journal of Immunology, Vol 125, Issue 3 1240-1242, Copyright © 1980 by American Association of Immunologists

ARTICLES

Induction of murine B cell proliferation by insolubilized anti- immunoglobulins

E Pure and E Vitetta

This study demonstrates that intact antibodies specific for mu, delta, or light chains when coupled to Sepharose are effective in delivering proliferative signals to B cells. Furthermore, using Sepharose-coupled anti-delta antibodies, we have shown that hybridoma anti-delta (that is not active as soluble protein) is as effective as rabbit anti-delta in activating murine B cells. However, antibodies directed against two other surface molecules, I-A and H-2K, were not mitogenic. Thus, sIgM and sIgD are comparable in their ability to transmit a proliferative signal to the B cell and sIg seems to play a unique role in this regard.


This article has been cited by other articles:


Home page
 J. Immunol.Home page
R. Thyagarajan, N. Arunkumar, and W. Song
Polyvalent Antigens Stabilize B Cell Antigen Receptor Surface Signaling Microdomains
J. Immunol., June 15, 2003; 170(12): 6099 - 6106.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1980 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1980 by The American Association of Immunologists, Inc. All rights reserved.