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The Journal of Immunology, 1979, 123: 947-948.
Copyright © 1979 by The American Association of Immunologists, Inc.
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Genetic Mapping of the Locus Controlling Structural Variations of Murine C3 in the Chromosome 171

Shunnosuke Natsuume-Sakai, Junichiro Hayakawa, Shigetoyo Amano and Morinobu Takahashi

From the Department of Immunobiology, Cancer Research Institute, and the Institute of Experimental Animals, Kanazawa University, Kanazawa, Japan 920

Abstract

Backcross progeny, (NC x TF/GnLe)F1 x TF/GnLe, was tested for C3 allotype controlled by C3-1 and the expression of mutant gene tf, repeated loss and regrowth of hair. The recombination frequency between these two loci both located in chromosome 17 of the mouse was 24%. Taken together with our previous linkage data, C3-1 is now localized to a position 11 cm more distal than H-2 on chromosome 17.

Footnotes

1 This work was supported in part by grants from the Ministry of Education and the Ministry of Health and Welfare, the Government of Japan.






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