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Beyond Cellular Immunology

From the Webb- Waring Lung Institute and the Department of Microbiology and Immunology, the University of Colorado Medical Center, Denver, Colorado 80262

Abstract

Over the past 20 years we have seen the explosive development of a new scientific discipline, cellular immunology. At least 60% of the articles in our Journal and more than 60% of the allergy and immunology grants received or awarded by the National Institute of Allergy and Infectious Diseases in the past year involve experiments with lymphocytes and macrophages. This would have amused and pleased Dr. Gerald B. Webb, (Fig. 1), the first president of our Society. Dr. Webb was an early advocate of cellular immunology, but in his day this approach to immunity was not very popular; the humoral immunologists and serologists had the upper hand.

In the next few minutes I plan to review for you the origin and growth of cellular immunology and show how the very factors that led to its explosive development should be instrumental in creating a still newer discipline.

First a note about the origin of the word immunology.