HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Landen, B. Articles by Dierich, M. P. Search for Related Content PubMed Articles by Landen, B. Articles by Dierich, M. P.

Identity of C3- and C5-Receptors on Lymphoid Cells¹

From the Institute for Medical Microbiology, Johannesburg-Gutenberg Universität Mainz, West Germany

Abstract

Tannic acid-treated SRBC, incubated with increasing concentrations of C5 (E^tan-C5) can be attached to C3 receptor-carrying (Raji) cells. This binding is dependent on the amount of C5 on E^tan-C5 and can be inhibited by pretreatment of the Raji cells with either C5 or C3. Similar inhibition by soluble C3 and C5, respectively, is obtained for the interaction between Raji cells and E^tan-C3. In addition, the immune adherence reaction between E^hum and EAC1423b could be blocked by previous treatment of E^hum with C5 or with C3. These results suggest the presence of binding sites for C5 on lymphoid cells and their identity with C3 receptors.

Footnotes

¹ The work was supported by the Deutsche Forschungsgemeinschaft (SFB 107, Di A5).

² Correspondence to: M.P.D. Institute for Medical Microbiology, Augustusplatz, D-6500 Mainz, FRG.