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Herpes Simplex-Raji(A44), a New Cell Line for Serologic Testing by Immunofluorescence

Laboratoire de Virologie, Centre Hospitalier Universitaire, Grenoble, France and the International Agency for Research on Cancer, Lyon, France

Abstract

An IF technique for the detection of HSV antibodies by using a lymphoblastoid cell line, Raji(A44), which continuously produce a constant amount of HSV antigen, is described. If and IH tests were found to be similar with respect to sensitivity and reproducibility. Sero-conversions detected by the CF test were detected with this cell line. The Raji(A44) line (cells in suspension) can be routinely used for the diagnosis of HSV infection.

This article has been cited by other articles:

				J. Seigneurin, C Desgranges, D Seigneurin, J Paire, J. Renversez, B Jacquemont, and C Micouin Herpes simplex virus glycoprotein D: human monoclonal antibody produced by bone marrow cell line Science, July 8, 1983; 221(4606): 173 - 175. [Abstract] [PDF]