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The Journal of Immunology, 1976, 117: 106-109.
Copyright © 1976 by The American Association of Immunologists, Inc.

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Studies on the Terminal Stages of Antibody-Complement Mediated Killing of a Tumor Cell

III. Effect of Membrane Active Agents

Michael D. P. Boyle, Sarkis H. Ohanian and Tibor Borsos

From the Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014

Abstract

A comparison of the events leading from T* to dead cells and E* to E ghost and hemoglobin was made. Transformation of T* to dead cells was inhibitable by EDTA, NaF, histamine, DMSO, cytochalasin B and 3'5' cAMP. Transformation of E* to E ghost and hemoglobin was only inhibited by EDTA.







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