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The Journal of Immunology, 1975, 114: 779-781.
Copyright © 1975 by The American Association of Immunologists, Inc.

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Rat Cell Surface Antigens

II. Isolation of a Minor Histocompatibility Antigen1

Gerald N. Callahan and Charles W. Dewitt

From the Department of Pathology, College of Medicine, University of Utah, Salt Lake City, Utah 84132

Abstract

A cell surface antigen was isolated from soluble extracts of rat lymphoid cells. Molecular weight of the purified antigen was estimated by SDS gel electrophoresis to be 10 to 20,000 daltons. Physical as well as immunologic properties of this antigen do not resemble those of any known antigenic product of the major histocompatibility locus of the rat. It is therefore proposed that it is a rat minor histocompatibility antigen.

Footnotes

1 This work was supported by Grants AI 11956 and AI 08934 from the National Institute of Allergy and Infectious Diseases.







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