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Radioresistance of Some Biologic Properties of Mouse Mast Cells¹

Department of Pathology New York University School of Medicine, New York, New York 10016

Abstract

Mast cells taken 11 or 25 days after a sublethal irradiation (540 R) formed rosettes with antibody-coated sheep erythrocytes in the same number as in control non-irradiated mice. The threshold of passive cutaneous anaphylaxis reactions with mouse IgG1 or IgE antibody 2 to 7 days after irradiation was the same in sublethally (540 R), or lethally (780 R), irradiated mice as it was in controls.

Footnotes

¹ This investigation was supported by National Institutes of Health Grant AI-03075-15 and by the Cancer Institute, Inc., New York, New York.

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