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The Journal of Immunology, 1973, 110: 1452-1453.
Copyright © 1973 by The American Association of Immunologists, Inc.

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C3 Split Products Inhibit the Binding of Antigen-Antibody-Complement Complexes to B Lymphocytes1

Aline Eden, Celso Bianco, Victor Nussenzweig and Manfred M. Mayer

From the Department of Pathology New York University School of Medicine, New York, New York 10016, and the Department of Microbiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

Abstract

The interaction between EAC and bone marrow derived, thymus independent lymphocytes depends on the amount of C3 present on the EAC and is inhibited by split products of C3.

Footnotes

1 This investigation was supported by National Institutes of Health Grants AI-08499, GM-00127, and 5 R01 AI-02566-14 and National Science Foundation Grant GB 7406 x 3.







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