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The Journal of Immunology, 1973, 110: 1340-1344.
Copyright © 1973 by The American Association of Immunologists, Inc.
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Demonstration of Proliferation by Guinea Pig and Rabbit Bone Marrow-Derived Lymphocytes in Vitro in Response to Stimulation by Anti-Immunoglobulin Antisera

Gerald J. Elfenbein, Michael R. Harrison and Rose G. Mage

From the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20014

Abstract

We have employed simultaneous complement receptor lymphocyte rosette and radioautographic techniques to investigate the proliferative response of guinea pig lymph node and rabbit peripheral blood bone marrow-drived (B) lymphocytes to stimulation with anti-immunoglobulin antisera. We have shown directly that all of the proliferative response due to anti-immunoglobulin antisera occurred in the complement receptor lymphocyte (B cell) subpopulation.






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