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The Journal of Immunology, 1973, 110: 1146-1150.
Copyright © 1973 by The American Association of Immunologists, Inc.

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Macrophage migration inhibition in response to experimental mycoplasma pneumoniae infection in the hamster1

Gunnel Biberfeld2

From the National Bacteriological Laboratory and Department of Immunology, Karolinska Institutet, Stockholm, Sweden

Abstract

The migration of peritoneal exudate cells collected from hamsters experimentally infected with M. pneumoniae was inhibited in the presence of M. pneumoniae antigen. Migration inhibition was demonstrable 1 week after intranasal inoculation of the hamsters with M. pneumoniae organisms and reached a peak 2 to 3 weeks after inoculation. The migration inhibition test became positive before specific CF antibodies had appeared.

Footnotes

1 This work was supported by grants from the Swedish Medical Research Council (Project 16X-2380) and the Swedish National Association against Heart and Chest Diseases.

2 Address correspondence to: Dr. Gunnel Biberfeld, The Stockholm county council central microbiological laboratory, Box 177, 101 22 Stockholm 1 Sweden.







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