HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Di Pauli, R. Search for Related Content PubMed Articles by Di Pauli, R.

Genetics of the Immune Response

I. Differences in the Specificity of Antibodies to Lipopolysaccharides Among Different Strains of Mice

From the Immunology Unit, Division of Biology, University of Konstanz, Konstanz, Germany

Abstract

The antibody response to Salmonella lipopolysaccharides was investigated at the cellular level by means of a hemolytic plaque test combined with inhibition. With these techniques the cross-reactivity of antibodies produced by single cells could be studied. A difference in the ability of mouse strains to produce typical specific antibodies was found. This strain difference resides in the process that recognizes the antigen and is not due to a lack of antibody-producing precursor cells. The role of receptors in the recognition of lipopolysaccharide antigens is discussed.