HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Colten, H. R. Articles by Alper, C. A. Search for Related Content PubMed Articles by Colten, H. R. Articles by Alper, C. A.

Hemolytic Efficiencies of Genetic Variants of Human C3¹

From the Immunology Division, Department of Medicine, Children's Hospital Medical Center, the Blood Grouping Laboratory, and the Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115

Abstract

The hemolytic efficiency of the genetic variants of the third component of complement (C3), native C3 in serum and highly purified C3 were estimated. The specific hemolytic activities of each of the partially purified variants were similar to that of C3 in whole serum but only about 20% that of highly purified C3. In the highly purified preparation, approximately 300 C3 molecules were bound for each hemolytic site.

Footnotes

¹ This work was supported by Grants AI-05877 and AM-13855 from the United States Public Health Service.