HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Stark, J. M. Articles by Spitznagel, J. K. Search for Related Content PubMed Articles by Stark, J. M. Articles by Spitznagel, J. K.

Immunogenicity of Bovine Serum Albumin and Its Oligopolymers in CBA Mice

Department of Bacteriology and Immunology, The School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27514

Abstract

The monomer of bovine serum albumin (BSA) and its oligopolymers have been examined as immunogens in female CBA mice. When given intravenously the greatest ability not only to stimulate antibody formation but also to induce tolerance resided in the monomer. All forms were equally immunogenic if presented in complete Freund's adjuvant.

These findings are discussed in relation to the elimination rate which became faster with increasing molecular size of the BSA immunogen.

Footnotes

¹ MRC Traveling Research Fellow on leave of absence from University Department of Bacteriology and Immunology. Western Infirmary, Glasgow, W.1. Scotland.