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The Journal of Immunology, 1972, 108: 782-784.
Copyright © 1972 by The American Association of Immunologists, Inc.
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A Study on the Immunoglobulin Class of the Anti-A1 Isoagglutinin

H. Plischka and E. Schäfer

Ernst-Rodenwaldt-Institute of Hygiene and Experimental Medicine, Department of Serology, 54 Koblenz, Germany

Abstract

It is shown by DEAE-cellulose chromatography, gel filtration on Sephadex G-200 and by density gradient ultracentrifugation that there are IgG isoantibodies in O sera, which can differentiate between A1 and A2 red cells quite well. From this it is concluded that the difference between A1 and A2 red cells must be qualitative.






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