HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Yuill, T. M. Articles by Buescher, E. L. Search for Related Content PubMed Articles by Yuill, T. M. Articles by Buescher, E. L.

Nonspecific Arbovirus Hemagglutinin Inhibitors in Turtle Sera

From the Department of Virus Diseases, Walter Reed Army Institute of Research, Washington, D. C. 20012

Abstract

The hemagglutination-inhibition (HI) test has been used extensively to document the presence of antibodies to various arboviruses in man and animals; its interpretation assumes that the observed HI reaction is due to viral antibody. That this is not always so has been reported for large numbers of hens (50% of 422 tested) and "antibody" for western equine encephalitis (WEE) virus (1), but only for a small number of turtles (1% to 2% of 166) reacting nonspecifically with eastern equine encephalitis (EEE) virus (2). During a period of EEE virus dissemination on the Eastern Shore of Maryland, substantial numbers of turtle sera inhibited EEE but not WEE hemagglutinins. Moreover, seroconversions in some of these turtles led us to believe initially that they might be naturally infected. While subsequent tests of these sera showed no neutralizing antibody, the apparent seroconversions by HI test were unexplained.

Footnotes

¹ Present address: Department of Veterinary Science, University of Wisconsin, Madison, Wisconsin 53706.