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Antigenic Markers on Cells Leaving Calf Thymus by Way of the Efferent Lymph and Venous Blood¹

From the Harvard Medical School, Boston, Massachusetts, the Medical Department, Brookhaven National Laboratory, Upton, New York, and the Department of Microbiology, Yale University, New Haven, Connecticut

Abstract

A significant proportion of lymphoid cells which leave the calf thymus by the efferent lymph or blood have thymus-specific antigen (BTA) in their cell membrane. These were found to be larger than the majority of BTA-positive cells within the thymus. Similar cells were not observed in arterial blood, thoracic duct lymph or prescapular lymph nodes.

Footnotes

¹ This work was supported by United States Public Health Service Grants AI-06112 and AI-06455, and the United States Atomic Energy Commission.

² Harvard Medical School, Boston, Massachusetts 02115.

³ Medical Department, Brookhaven National Laboratory, Upton, L.I., New York 11973.

⁴ Department of Microbiology, Yale University, New Haven, Connecticut 06510.