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The Journal of Immunology, 1970, 105: 1031-1032.
Copyright © 1970 by The American Association of Immunologists, Inc.
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Streptococcal M Protein Vaccines, Rheumatic Fever and Human Histocompatibility Antigens1

Eugene N. Fox and Raymond D. A. Peterson

From the Variety Club Research Center and the Sprague Regional Tissue Typing Center of La Rabida Children's Hospital and Research Institute, University of Chicago, Chicago, Illinois 60649

Abstract

Within the limits of our techniques, we could not demonstrate any serologic cross-reactions between streptococcal M proteins and human histocompatibility antigens, nor could we detect antibodies to human transplantation antigens in persons during the acute or convalescent phases of rheumatic fever, or subsequent to the administration of streptococcal M protein vaccine.

Footnotes

1 This work was supported in part by a contract (PH-43-68-83) of the Vaccine Development Branch, National Institutes of Allergy and Infectious Diseases, National Institute of Health.






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