HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Intorp, H. W. Articles by Witebsky, E. Search for Related Content PubMed Articles by Intorp, H. W. Articles by Witebsky, E.

Antigens of Normal and Atherosclerotic Intima¹

From the Department of Microbiology, State University of New York at Buffalo, School of Medicine, Buffalo, New York 14214

Abstract

Rabbit antisera to normal and atherosclerotic intima of human aorta were used to compare the antigenic composition of these tissues. The antigen characteristic for normal tissue was a thermolabile component with fast electrophoretic mobility. This component was considerably reduced in amount in atherosclerotic plaques. Atherosclerotic lesions contained two "novel" antigens, virtually absent from normal intima. These antigens were identified as fibrinogen and C-reactive protein, respectively.

Footnotes

This investigation was supported by United States Public Health Service Research Grant CA-02357 from the National Cancer Institute.

² Recipient of a NATO Research Grant and a Research Fellowship from the United Health Foundation of Western New York.