The JI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

The Journal of Immunology, 1969, 102: 194-205.
Copyright © 1969 by The American Association of Immunologists, Inc.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Glassock, R. J.
Right arrow Articles by Dixon, F. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Glassock, R. J.
Right arrow Articles by Dixon, F. J.

Autologous Immune Complex Glomerulonephritis

III. Studies on Cellular and Parabiotic Transfer1

Richard J. Glassock2, J. Ian Watson3, T. S. Edgington4 and Frank J. Dixon

From the Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California 92037

Abstract

Transfer of lymphoid cells from rats with autologous immune complex nephritis induced by intraperitoneal immunization with renal tubular antigen consistently failed to produce disease in normal rats of the same inbred strain. On the contrary, transfer of isologous lymphoid cells from rats with disease induced by intracutaneous and footpad immunization produced a similar, although clinically mild disease, which appeared only after a latent period equal to that needed for the active induction of disease. These observations and those concerning the nature of parabiotic transfer of this disease are consistent with but do not conclusively prove the concept that active immunization of the cell recipient by transferred antigen may play a role in the transfer phenomenon along with any antibody which may be formed by the transferred cells.

Footnotes

This is Publication 290 from the Department of Experimental Pathology, Scripps Clinic and Research Foundation; supported in part by United States Public Health Service Grant A1-07007 and AEC Contract AT-(04-3)-410.

2 Work performed while on leave of absence from Cardio-Renal Section, Peter Bent Brigham Hospital; supported by United States Public Health Service Grant ITI-AI-301-01. Present address: Harbor General Hospital, Torrance, California.

3 Present address: Royal Victoria Hospital, Montreal, Canada.

4 Supported by United States Public Health Service Training Grant 5T1-GM-683.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1969 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1969 by The American Association of Immunologists, Inc. All rights reserved.