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The Journal of Immunology, 1968, 101: 1248-1252.
Copyright © 1968 by The American Association of Immunologists, Inc.
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Light Chain Determinants of Exocrine Isoagglutinins1

Nicolas Costea, Vincent Yakulis, John Schmale and Paul Heller

Department of Medicine, University of Illinois College of Medicine and the Veterans Administration West Side Hospital, Chicago, Illinois 60612

Abstract

Exocrine (IgA) isoagglutinins with specificity to the A-erythrocyte antigen contain both K and L type IgA subunits which retain agglutinating activity. Reductive depolymerization using NaBH4 results in the formation of free transport pieces and 7 S subunits.

Footnotes

This study was supported by Grant AI-07085 from the National Institutes of Health, United States Public Health Service and by Veterans Administration Medical Research Funds.






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