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The Antigenic Determinants of the Variable Half of a Bence-Jones Protein of Type L¹

International Laboratory of Genetics and Biophysics, Naples, Italy

Abstract

The antigenic determinants of a fragment of a Bence-Jones protein of type L corresponding to the NH₂-terminal variable half of this protein were studied. Information about the number of these antigenic determinants, their distribution among Bence-Jones proteins of type K and L and their presence in human IgG immunoglobulin was obtained. The best experimental conditions for identifying these immunologic "markers" in the variable half of the light chains of immunoglobulins were described.

Footnotes

¹ This work was carried out under the association EURATOM CNR CNEN Contract no. 016 61 12 BIAI.