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Gl and Rabbit Antibodies1
Department of Pathology, New York University School of Medicine, New York
Abstract
PCA reactions were produced in guinea pigs with rabbit
G- and guinea pig
G1-antibodies. The histologic picture of PCA reactions with guinea pig
G1 in guinea pigs is similar to the reaction produced with rabbit antibodies. PCA reactions with rabbit and guinea pig
G1-antibodies were partially inhibited by an antihistamine (Neo-Antergan) to the same degree. Depletion of PMN did not diminish the PCA reactions with either antibody. It has been concluded that PMN infiltration is a consequence, and not the determining factor, of PCA reactions in guinea pigs.
Footnotes
This investigation was supported by National Institutes of Health Grant AI-03075-08, and by the Health Research Council, City of New York under Contract I-140.
2 Health Research Council Career Scientist of the City of New York.
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